Clinical Practice Guidelines of the Russian Society for the Study of the Liver, the Russian Gastroenterological Association, the National Scientific Society of Infectious Disease Specialists for the Diagnosis and Treatment of Chronic Hepatitis C

Аim: diagnosis and treatment algorithms in the clinical recommendations intended for general practitioners, gastroenterologists, infectious disease specialists, hepatologists on of chronic hepatitis C are presented. Summary. Chronic viral is a socially significant infection, incidence which Russian Federation remains significantly high. Over past 10 years, great progress has been made — direct acting antiviral drugs have appeared. The spectrum their effectiveness allows to achieve sustained virological response more than 90 % cases, even groups that were not previously considered as candidates therapy or difficult treat patients receiving renal replacement therapy, after liver transplantation (or other organs), at stage decompensated cirrhosis, HIV co-infected, etc. Interferons excluded from due low wide range adverse events. indications expanded, namely, fact confirmation replication. terms dispensary observation without cirrhosis reduced (up 12 weeks end therapy). Also, these present approaches active screening risk groups, preventive rehabilitation measures treatment. Conclusion. Great success achieved C. In most eradication HCV infection real task liver, with impaired function, co-infection, solid organs transplantation.